Publikationen

responsif GmbH / november AG

Schumacher, T., Ruehland, C., Schultheiss, C., Brinkman, M., Roedel, F., Reiser,COA, Hess, J.,Reichel, C. (2007) Advanced Antigen Delivery of Murine Survivin: Chimeric Virus-Like Particles in Cancer Vaccine Research
International Journal of Biomedical Science, Sept; 3 (3), 199- 205

Bickert T, Wohlleben G, Brinkman M, Trujillo-Vargas CM, Ruehland C, Reiser CO, Hess J, Erb KJ. (2007) Murine polyomavirus-like particles induce maturation of bone marrow-derived dendritic cells and proliferation of T cells.
Med Microbiol Immunol. Mar;196(1):31-9. Epub 2006 Aug 18.

Neugebauer M, Walders B, Brinkman M, Ruehland C, Schumacher T, Bertling WM, Geuther E, Reiser CO, Reichel C, Strich S, Hess J. (2006) Development of a vaccine marker technology: display of B cell epitopes on the surface of recombinant polyomavirus-like pentamers and capsoids induces peptide-specific antibodies in piglets after vaccination.
Biotechnol J. Dec;1(12):1435-46.

Ruehland, C. Reichel, C., Neugebauer, M., Strich, S., Bertling, W.M., Reiser, C.O.A., Hess, J. (2006) ImmunoTrack: the novel antibody-based technology for tracing in animal health.
Biotechnol J. Jun;1(6):625-32.

Reichel, C., Brinkman, M., Reiser, C.O.A., and Hess J. (2006) Heterologous virus-like-particles: recombinant nanosystems as versatile antigen delivery devices for immune intervention.
Current Nanoscience, 2 (4), 295-309

Raschke, A., Strich, S., Huppke, S., Neugebauer, M., Geuther, E., Bertling, W., Walders, B., Reiser, C.O.A., and Hess, J. (2006) Induction and detection of long-lasting peptide-specific antibody responses in pigs and beef cattle: a powerful technology for tracing meat processing chains from stock farmers to sales counters.
Food Control 17: 65.

Reichel, C., Ruehland, C., Reiser, C.O.A., and Hess J. (2005) Protein-based nanosystems: virus-like-particles in modern vaccine development.
Journal of Biomedical Nanotechnology; 2, 1 –5

Brinkman, M., Walter, J., Grein, S., Thies, M.J., Schulz, T.W., Herrmann, M., Reiser, C.O.A., and Hess J. (2005) Beneficial therapeutic effects with different particulate structures of murine polyomavirus VP1-coat protein carrying self or non-self CD8 T cell epitopes against murine melanoma.
Cancer Immunol Immunother . 54(6): 611.

Walders, B., Raschke, A., Neugebauer, M., Geuther, E., Bertling, W., Reiser, C.O.A., Buck, A., Strich, S., and Hess, J. (2004) Blending of conventional Mycoplasma pneumoniae vaccine with a positive marker: tracking of immunised pigs by peptide-specific antibodies raised to the marker component.
Res. Vet. Sci . 78(2): 135.

Abbing, A., Blaschke, U.K., Grein, S., Kretschmar, M., Stark, C.M.B., Thies, M.J.W., Walter, J., Weigand, M., Woith, D.C., Hess, J. and Reiser, C.O.A. (2004) Efficient Intracellular Delivery of a Protein and a Low Molecular Weight Substance via Recombinant Polyomavirus-Like Particles.
J. Biol. Chem., 279: 27410

Brinkman, M., Walter, J., Jennes, I., Neugebauer, M., Bertling, W., Grein, S., Thies, M., Weigand, M., Beyer, T., Herrmann, M., Reiser, C. and Hess, J. (2004) Recombinant murine polyoma virus-like-particles induce protective anti-tumour immunity.
Letters in Drug Design & Discovery , 1: 137.

Beyer, T., Herrmann, M., Reiser, C.O.A., Bertling, W.M. & Hess, J. (2001) Bacterial carriers and virus-like particles as antigen delivery devices: Role of dendritic cells in antigen presentation.
Current Drug Targets - Infectious Disorders, 1: 307.

Medizinische Klinik IV, Nephrologische Forschungslaboratorien, Universität Erlangen-Nürnberg

Goppelt-Struebe M, Fickel S, Reiser C.O.A. (2000)
The platelet-derived-growth-factor receptor, not the epidermal-growth-factor receptor, is used by lysophosphatidic acid to activate p42/44 mitogen-activated protein kinase and to induce prostaglandin G/H synthase-2 in mesangial cells.
Biochem. J. 345, 217-24

Goppelt-Struebe M, Hahn A, Stroebel M, Reiser C.O.A. (1999)
Independent regulation of cyclo-oxygenase 2 expression by p42/44 mitogen-activated protein kinases and Ca2+/calmodulin-dependent kinase.
Biochem. J. 339, 329-34

Reiser, C.O.A., Lanz, Th., Hofmann, F., Hofer, G., Rupprecht, H.D. und Goppelt-Struebe, M. (1998)
Lysophosphatidic acid-mediated signal transduction pathways involved in the induction of the early response genes prostaglandin G/H synthase-2 and Egr-1 - A critical role for the MAP kinase p38 and for Rho proteins -
Biochem. J. 330, 1107-1114.

Reiser, C.O.A. und Goppelt-Struebe, M. (1996)
Modulation of phospholipase D stimulation in c-src transfected mesangial cells.
J. Lipid Mediators Cell Signalling 15, 193-202.

Goppelt-Struebe, M., Reiser, C.O.A., Schneider, N. und Grell, M. (1996)
Modulation of tumor necrosis factor (TNF) receptor expression during monocytic differentiation by glucocorticoids.
Inflamm. Res. 45, 503-507.

Reiser, C.O.A., Marx, M., Hoppe, J. und Goppelt-Struebe, M. (1996)
Modulation of prostaglandin G/H synthase expression in mesangial cells transfected by pp60c-src proto-oncogene.
Exp. Cell Research 222, 304-311.

Lehrstuhl für Biochemie, Universität Bayreuth

Berchtold, H., Reshetnikova, L.S., Reiser, C.O.A., Schirmer, N.K., Sprinzl, M. und Hilgenfeld, R. (1993)
Crystal structure of active elongation factor Tu reveals major domain rearrangements.
Nature 365, 126-132.

Limmer, St., Reiser, C.O.A., Schirmer, N.K., Grillenbeck, N.W. und Sprinzl, M. (1992)
Nucleotide binding and GTP hydrolysis by elongation factor Tu from Thermus thermophilus as monitored by proton NMR.
Biochemistry, 31, 2970-2977.

Reshetnikova, L.S., Schirmer, N.K., Reiser, C.O.A., Berchtold, H., Storm, R., Hilgenfeld, R. und Sprinzl, M. (1992)
Crystals of intact elongation factor Tu from Thermus thermophilus diffracting to 1.45 Å resolution.
J. Crystal Growth 122, 360-365.

Park, H.J., Kreutzer, R., Reiser, C.O.A. und Sprinzl, M. (1992)
Molecular cloning and nucleotide sequence of the gene encoding a H2O2-forming NADH oxidase from the extreme thermophilic Thermus thermophilus HB8 and its expression in Escherichia coli.
Eur. J. Biochem. 205, 875-879.

Park, H.J., Reiser, C.O.A., Kondruweit, S., Erdmann, H., Schmid, R.D.und Sprinzl, M. (1992)
Purification and characterization of a NADH oxidase from the thermophile Thermus thermophilus HB8.
Eur. J. Biochem. 205, 881-885.

Reshetnikova, L., Reiser, C.O.A., Schirmer, N.K., Berchtold, H., Storm, R., Hilgenfeld, R. und Sprinzl, M. (1991)
Crystals of intact elongation factor Tu from Thermus thermophilus diffracting to high resolution.
J. Mol. Biol. 221, 375-377.

Schirmer, N.K., Reiser, C.O.A. und Sprinzl, M. (1991)
Effect of Thermus thermophilus elongation factor Ts on the conformation of elongation factor Tu.
Eur. J. Biochem. 200, 295-300.

Peter, M.E., Schirmer, N.K., Reiser, C.O.A. und Sprinzl, M. (1990)
Mapping the Effector Region in Thermus thermophilus Elongation Factor Tu.
Biochemistry 29, 2876-2884

Peter, M.E., Reiser, C.O.A., Schirmer, N.K., Kiefhaber, T., Ott, G., Grillenbeck, N.W. und Sprinzl, M. (1990)
Interaction of the isolated domain II/III of Thermus thermophilus elongation factor Tu with the nucleotide exchange factor EF-Ts.
Nucleic Acids Res., 18, 6889-6893

Buchbeiträge

Kondruweit, S., Erdmann, H., Park, H.J., Reiser, C.O.A., Sprinzl, M. und Schmid, R.D. (1991)
Preparation of a NADH oxidase for Biosensor applications.
GBF Monographs Series 17, Biosensors: Fundamentals, Technologies and Applications (Hrsg. Scheller, F. und Schmid, R.D.), VCH Publisher, Weinheim, 245-250.

Park, H.J., Kreutzer, R., Reiser, C.O.A., Schmid, R.D. und Sprinzl, M.
H2O2-forming NADH oxidase from Thermus thermophilus HB8 for cofactor recycling in biosensor applications: molecular cloning of the gene and its expression in Escherichia coli .
GBF Monographs Series 17, Biosensors: Fundamentals, Technologies and Applications, (Hrsg. Scheller, F. und Schmid, R.D.)250-251, VCH Publisher, Weinheim, 250-251.